Abstract
For several reasons Ascaris uterine epithelium is useful for the study of polyploidy. It shows a range of polyploid values which, when expressed as average nuclear DNA, correlate with variations in cytoplasmic ribonucleoprotein. The arrangement of the uterine epithelial cells in a single sheet consisting of large cells makes possible detailed analysis of cell function from end to end of the uterus. This possibility, coupled with the ability to study the uterine epithelium in both differentiating and adult animals, permits study of the function of single cells or discrete populations of cells during the development of polyploidy. Thus use of Ascaris uterine epithelium as an experimental system may yield important information concerning the significance of polyploidy in biological systems.
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