Abstract

The Use of Isotope Tracers to Study Intermediary Metabolism: Rudolf Schoenheimer

Highlights

  • Deuterium as an Indicator in the Study of Intermediary Metabolism

  • In addition to Schoenheimer and Karl Meyer, the author of a previous Journal of Biological Chemistry (JBC) Classic (1), many other European biochemists including Erwin Chargaff, Zacharias Dische, Heinrich Waelsch, and Erwin Brand benefited from positions and research support provided by Clarke

  • As Eugene Kennedy rightly reminded us (3) in describing Clarke’s account of the recruitment of these scientists to Columbia, “Clarke modestly omitted to mention that his own vision and humane instincts in welcoming these gifted refugees were by no means to be found in every American academic institution.”

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Summary

Introduction

Deuterium as an Indicator in the Study of Intermediary Metabolism. XI. Rudolf Schoenheimer (1898 –1941) pioneered the use of isotopes for the study of metabolism and transformed biochemistry. He worked with Karl Thomas in Leipzig for three years to extend his education and experiences with synthetic chemistry of biological molecules.

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