The use of Flumethrin-, Moxidectin- and Pyriproxyfen-based drug in spray formulation against Ixodid and Acariform ticks in dogs and cats

Abstract

The purpose of the research is to study the efficacy of Flumethrin-, Moxidectin- and Pyriproxyfen-based spray against Ixodid and Acariform ticks in dogs and cats.Materials and methods. The therapeutic efficacy of a multicomponent spray against Ixodid and Acariform ticks was evaluated in dogs and cats in the Podolsk Experimental Production Base of the VNIIP – FSC VIEV on 140 animals naturally infected with Ixodid and Acariform ticks. The animals were divided into an experimental group and a control group of 10 animals each. The experimental dogs and cats were given the study drug while the control animals were not given the drug. Clinical examinations at ixodidosis in dogs and cats were performed at 24 and 48 hours, and at 3 and 5 days after the start of the experiment. In Acariformes parasitism, a control examination and microscopy of deep skin scrapings taken at the healthy and affected skin interface were made using a scalpel at 7, 14, 21, 28 and 35 days after the start of the experiment, in treatment of sarcoptic mange, notoedric mange and demodicosis as well as scrapings from the auricle (distal part of the acoustic canal) in otodectic mange.Results and discussion. It was found that Flumethrin-, Moxidectin- and Pyriproxyfen-based spray had high therapeutic efficacy when used once, externally, against ixodid tick, and in the auricle twice with a 7-day interval against otodectic mange and externally 2–4 times with a 7-day interval against notoedric mange, sarcoptic mange and demodicosis in various disease forms in dogs and cats.