THE USE OF ANTIOXIDANTS IN TREATMENT OF PATIENTS WITH GINGIVITIS & CHRONIC PERIODONTIST (INTERVENTION STUDY).

Abstract

Background: The potential role of antioxidants in treatment of periodontitis, there is a recent interest about the relationship between antioxidants and periodontitis, so the present study was designed to prove this correlation. The aim of the present study was to investigate the effects of use of antioxidants as adjuncts in treatment of periodontitis. Materials and Methods: 75 subjects were divided into five groups: clinically healthy, gingivitis treated non surgically, gingivitis treated non surgically with antitoxins supplementation, periodontitis treated non surgically, periodontitis treated non surgically with antitoxins supplementation, groups were dividedaccording to Community Periodontal Index of Treatment Needs. At the baseline, periodontal attachment loss was recorded and scaling and root planning was performed in gingivitis and periodontitis groups. Antioxidants supplementations were administrated in the form of single daily dosage taken orally for two weeks. Saliva samples were collected at baseline, 15th day, 30th day, and 45th day for evaluation of uric acid levels. Results: Uric acid levels were significantly low in patients with more destructive periodontitis as compared to clinically healthy and gingivitis groups. As the treatment was initiated, significant increase in uric acid levels was observed as the time elapsed.Conclusion: the increase in salivary antioxidants levels was observed after administration of antioxidants therapy, therefore antioxidant therapy can be used as an adjunct to nonsurgical periodontal therapy.