Abstract

The prognosis for children with Wilms’ tumor (WT) has improved dramatically. During the last three decades, the National Wilms Tumor Study Group (NWTSG), the International Society of Pediatric Oncology (SIOP), and the United Kingdom Children’s Cancer Study Group (UKCCSG) conducted sequential studies of treatments for children with WT. The results will be reviewed in the light of long-term follow-up. Areas for future investigation will be identified.

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