Abstract

PSORIASIS is a familial disease of the skin characterized clinically by an increased production of abnormal scales, resulting from a marked hyperplasia of immature epidermal cells.1 2 3 4 5 6 7 8 9 10 Further evidence of the rapid rate of cell division is the elevated serum uric acid level and the large uric acid pool, reflecting the increased turnover of nucleic acids.Biochemical studies have revealed the incomplete removal of these acids, soluble proteins and other constituents that are normally degraded during keratinization.Psoriasis is a common condition, occurring in one to two per cent of the population. The average age of onset is in the second . . .

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