Abstract

Background: Peri-implantitis is a pathological condition characterized by an inflammatory process involving soft and hard tissues surrounding dental implants. The management of peri-implant disease has several protocols, among which is the chemical method HYBENX®. The aim of this study is to demonstrate the efficacy of HYBENX® in the treatment of peri-implantitis and to compare HYBENX® with other chemical agents used in the surgical treatment of peri-implantitis. Methods: The present study included a population of ten subjects with severe peri-implantitis. The procedure used in the study involves the application of HYBENX® after open-flap debridement. Each patient has been followed for 12 months after a single application of the decontaminant agent. Clinical and radiographical parameters were recorded at baseline, 3 months, and 12 months after treatment completion. Results: At baseline, a mean pocket probing depth (PPD) of 7.3 ± 0.5 mm and a mean clinical attachment level (CAL) of 8.8 ± 0.8 mm was recorded. An average residual PPD of 4.2 ± 0.5 mm and a mean CAL of 5.2 ± 0.8 mm were observed after 1 year. Additionally, the average of bone gain was about 3.4 mm, with a mean marginal bone level (MBL) change from 5.8 mm (baseline) to 2.4 mm (12 months). In total, 90% of the treated implants reached the success rate after the 1-year follow-up. Only in one case out of ten treated implants was resolution of the disease not achieved. Conclusion: Clinical improvements highlight that the procedure of open-flap debridement (OFD) + HYBENX® may be considered an effective technique in the treatment of peri-implantitis. From the results obtained, it can be concluded that the use of HYBENX® in the surgical treatment of peri-implantitis is promising. Overall, this protocol demands further studies to better understand the role and potential benefits of HYBENX® in the treatment of peri-implantitis.

Highlights

  • During the last few years, several branches of dentistry have undergone major developments, most notably implantology

  • The aim of this study is to demonstrate the efficacy of HYBENX® to decontaminate the implant surface, in the case of mucositis and in the case of peri-implantitis and to stimulate bone regeneration of the affected area

  • The present study has shown that the use of HYBENX® seems to keep under control peri-implantitis and may reduce clinical and radiographic parameters

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Summary

Introduction

During the last few years, several branches of dentistry have undergone major developments, most notably implantology. There are two types of infection: the first affects only soft tissue (peri-implant mucositis) while the second results in the loss of supporting bone (peri-implantitis) [4]. Periimplant mucositis is usually reversible and is characterized by swelling and erythema of peri-implant mucosa, associated with bleeding on probing and probing depth (PD ≥ 4 mm) without bone loss. Peri-implantitis is a pathological condition concerning all peri-implant tissues, characterized by progressive bone loss around implants. The clinical signs of peri-implantitis are deep probing depth (≥6 mm), bleeding on probing (BOP+ ), radiographic evidence of bone loss and/or suppuration [5]. Peri-implantitis is a pathological condition characterized by an inflammatory process involving soft and hard tissues surrounding dental implants. The aim of this study is to demonstrate the efficacy of HYBENX® in the treatment of peri-implantitis and to compare HYBENX® with other chemical agents used in the surgical treatment of peri-implantitis

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