Abstract
Objective: to assess the efficacy of a lipid extract of the New Zealand green-lipped mussel, Perna canaliculus in rheumatoid and osteoarthritis and compare it with green-lipped mussel powder. Design: A double-blind 3-month parallel comparison of the two preparations and a further 3-month period of lipid extract for all patients. Setting: The out-patient department of the Glasgow Homoeopathic Hospital. Interventions: Stabilized green-lipped mussel powder, 1150 mg/day and the derived lipid extract, 210 mg/day. Main Outcome Measures: Articular index of joint tenderness (AI), morning stiffness (limbering-up-time, LUT), grip strength in each hand, visual analogue scale of pain (VA) and functional index (FI). Results: Seventy six percent of rheumatoid and 70% of osteoarthritic patients benefitted. AI, LUT and FI improved significantly by 3 months. The two preparations appeared equally efficacious. One patient experienced fluid retention and one developed nausea. There were no other adverse reactions. Conclusion: Both the stabilized freeze-dried mussel powder and its derived lipid extract are effective in reducing pain, swelling and stiffness and in improving functional index in rheumatoid arthritis and osteoarthritis.
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