Abstract
ABSTRACT Decreased weight gains, lowered feed efficiency, and hepatonephrotoxicity were observed in rats fed diets of ten percent Chrozophora obliqua (Del.) Juss. or ten percent Francoeuria crispa (Forssk.) Cass. leaves as compared with control rats on diets without tissue from these plants. The noted changes, accompanied by anemia and leucopenia, could be correlated with increased AST and GGT activity, increased concentrations of cholesterol and urea, decreased levels of total protein, plus other alterations in serum constituents as compared with serum constituents in rats on a control diet. Rats fed a 1:1 mixture (5% + 5%) of leaves from these plants in the diet were more seriously affected than rats fed individual leaf tissues in the diet.
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