Abstract

1. An attempt was made to discover what factor or factors are responsible for the observed differences among individuals of a pure line of Paramecia and Didinia living in the same culture medium; e.g., hay infusion. What are the differences in a protozoan cell which cause difference in response to apparently identical external conditions at different times?2. Survival time (resistance) of Paramecia and Didinia in solutions of KCN was selected and used as an index because of the generally supposed relation of the toxic action of KCN to the rate of oxidation in cells.3. All the data on survival time of Paramecium and Didinium were obtained by observations on individual cells and not by estimating the average survival time of large numbers of cells as is usual in such experiments. In this way the variation in resistance of the cell at different times during the period between cell divisions was followed accurately and is summarized in curves.4. The cessation of movement of Paramecium is a less variable end ...

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