Abstract

Abstract The histidine/Mn3O4/CdTe quantum dots composites (HMQ) with good MRI/fluorescent imaging and absorbance performance have been prepared based on peptide guiding biomimetic mineralization method, on which peptide served as a carrier to guide the formation of Mn3O4 and CdTe quantum dots. The fluorescence of HMQ could be quenched by malachite green (MG), whereas the magnetic resonance signal (T1-MRI) enhanced. Also, there are linear correlation between concentrations of MG added and the fluorescence intensity decreasing of HMQ (F0/F), the detection range is 0.06851 - 1.096 nmol/L, and LOD is 0.02750 nmol/L. Corresponding T1WI detection range is 13.7 - 95.9 nmol/L, and the LOD is 7.617 nmol/L. Furthermore, the fluorescence quenching spectra of HMQ adopted by MG have analyzed, of which data fit well with the law of pseudo-second-order kinetic, indicates as prepared HMQ has good absorption property. So HMQ could be used as an MRI/fluorescent dual sensor for detection of MG.

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