Abstract
Modern systemic therapy with chemotherapy, targeted therapy and immunotherapy has led to asignificant improvement in the overall survival in many tumor diseases over the past 15years. Thus, the surgical treatment of lung metastases and lymph node metastases is not only valuable to achieve acure for selected tumors but it can and must be used to eliminate tumor growth peaks in the case of acircumscribed progression. These can be an expression of tumor heterogeneity that cannot be achieved by systemic therapy. Depending on the dynamics and extent of the metastasis, the therapeutic approach must be individually decided in the tumor board.
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