Abstract

Background and Objectives: Generally, squamous cell carcinoma has a poor prognosis due to its tendency towards local invasion and subsequent metastasis, which is mediated by multiple factors and angiogenesis. Hepatocyte growth factor (HGF) is a potent mitogen for epithelial cells that regulates cell proliferation, migration, survival tumour angiogenesis and invasiveness. The aim of presented study was to determine serum concentration of HGF in patients with oral squamous cell carcinoma before and after initial treatment.

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