The role of nanotechnology in the future of orthopedics

Abstract

Event Abstract Back to Event The role of nanotechnology in the future of orthopedics Fares E. Sayegh1* 1 Aristotle University of Thessaloniki, Department of Orthopaedics, Greece Osteoarthritis (O.A) of the joints is defined as a progressive degenerative bone joint disease. It is the most common form of arthritis, and it is known as the “wear and tear” arthritis. It is caused by a breakdown of the joint cartilage, it is not a rare disease and it affects elder people in their 50s and 60s. 25% of patients with osteoarthritis cannot cope with their daily activities, may present depression and social isolation and may have difficulty with ambulation. The diagnosis of late O.A is easy but early detection of O.A and the ability to monitor the progression of disease are important for developing effective therapies and preventive drugs. Besides conservative therapy, surgery is the treatment of choice for severe O.A of the joints. Total joint arthroplasty is one of the most popular surgical procedures performed by the orthopaedic surgeon for bone joint diseases. Failure of a total joint arthroplasty may be mainly due to infections, or to loosening of the prosthesis. The result of such complications are disastrous to the patient and the revision of such surgery is costly and requires highly demanding surgical techniques. In such situations what we need is suitable and competent surgeons as well as suitable compatible implants. We need biomaterials with physico-chemical properties that could recognize and manipulate properly the bone cell. Novel biomaterials can be fabricated into nanostructures that simulate the native hierarchical structure of the bone and as it is shown, nanoscale materials represent an important growing area of research that may improve bonding between an implant and surrounding bone and may reduce the rate of failure of such surgical orthopaedic implants. Keywords: Nanotechnology, Orthopedics, Osteoarthritis, Joints Conference: 8th Southeast European Congress on Xenobiotic Metabolism and Toxicity - XEMET 2010, Thessaloniki, Greece, 1 Oct - 5 Oct, 2010. Presentation Type: Oral Topic: Nanopharmacology / Nanomedicine Citation: Sayegh FE (2010). The role of nanotechnology in the future of orthopedics. Front. Pharmacol. Conference Abstract: 8th Southeast European Congress on Xenobiotic Metabolism and Toxicity - XEMET 2010. doi: 10.3389/conf.fphar.2010.60.00194 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 05 Mar 2011; Published Online: 04 Nov 2010. * Correspondence: Dr. Fares E Sayegh, Aristotle University of Thessaloniki, Department of Orthopaedics, Thessaloniki, Greece, fsayegh@auth.gr Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Fares E Sayegh Google Fares E Sayegh Google Scholar Fares E Sayegh PubMed Fares E Sayegh Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.