Abstract
Healthcare-associated infections (HAI) is an increasing global problem all over the world. Multidrug-resistant (MDR) pathogens, including carbapenem-resistant Gram-negative Enterobacterales, Pseudomonas spp. and Acinetobacter spp. have become common causes of HAI, such as central line-associated bloodstream infections (BSIs), catheter-associated urinary tract infections (UTIs), surgical site infections (SSIs) and ventilatory associated pneumonia (VAPs). These infections increase not only mortality but also healthcare
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