Abstract
The review presents data on the causes of dysregulation of calcium metabolism and its association with the main elements of the cardiovascular continuum. Particular attention was paid to its role in the regulation of endothelial function, systemic inflammation, myocardial contractility, lipid and carbohydrate metabolism, the disruption of which determines the initiation and progression of diseases such as essential hypertension and chronic heart failure. We also systematized data on the role and methods of calcium dysmetabolism correcting in the prevention and treatment of these pathologies.
Highlights
Государственная образовательная организация высшего профессионального образования Донецкий национальный медицинский университет имени М
Particular attention was paid to its role in the regulation of endothelial function, systemic inflammation, myocardial contractility, lipid and carbohydrate metabolism, the disruption of which determines the initiation and progression of diseases such as essential hypertension and chronic heart failure
We systematized data on the role and methods of calcium dysmetabolism correcting in the prevention and treatment of these pathologies
Summary
Государственная образовательная организация высшего профессионального образования Донецкий национальный медицинский университет имени М. Дополнительными факторами, влияющими на метаболизм макронутриента, особенно, у пациентов пожилого и старческого возраста, являются эссенциальная гипертензия (ЭГ) и ХСН, которые могут приводить к снижению реабсорбции Ca как путем нейрогуморальной активации и ретенции натрия и воды, так и в связи с применением петлевых диуретиков [3].
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