Abstract

Purpose: The aim of this study was to determine the prevalence of thyroiditis, nodular goiter, and thyroid cancer in small, normal, and large thyroids. Methods: Thyroid volume (TV) was measured by ultrasonography (US) in 583 adults and TV was divided into 3 groups: small (volume 40 ml). All patients underwent US-guided fine-needle aspiration biopsy (FNAB) and cytological diagnoses were divided into 6 groups: thyroiditis, nodular goiter, nodular goiter and thyroiditis, indeterminate, malignant, and inadequate. Results: In small thyroids (N=93), there were 42 (45%) diagnoses of thyroiditis, 42 (45%) diagnoses of nodular goiter, and one diagnosis (1%) of papillary carcinoma. In normal thyroids (N=101), there were 16 (16%) diagnoses of thyroiditis, 68 (67%) diagnoses of nodular goiter, and 4 (4%) diagnoses of papillary carcinoma. In large thyroids (N=389) there were 46 (12%) diagnoses of thyroiditis, 306 (79%) diagnoses of nodular goiter, and 8 (2%) diagnoses of thyroid carcinoma (6 papillary and 2 anaplastic). There was a statistically significant (p 0.05) relationship between TV and cytological diagnosis of thyroid carcinoma. Conclusions: Our results show a high prevalence of cytological diagnoses of thyroiditis in small thyroids, a high prevalence of cytological diagnoses of nodular goiter in large thyroids, and no relationship between TV and the cytological diagnosis of thyroid carcinoma.

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