The Relationship Between Obesity and Hypertension in Adolescents

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Obesity and hypertension are increasingly prevalent among adolescents, and both conditions are interrelated with significant long-term health consequences. This review examines the relationship between obesity and hypertension in adolescents, synthesizing findings from recent studies. Research indicates that obesity, particularly excessive visceral fat accumulation, leads to increased vascular resistance and activation of the renin-angiotensin-aldosterone system, contributing to elevated blood pressure. Genetic factors, along with insulin resistance and metabolic dysfunctions, further exacerbate the risk of developing hypertension in obese adolescents. Additionally, unhealthy dietary habits and insufficient physical activity are major contributors to obesity, which in turn increases the likelihood of hypertension. Studies have shown that interventions targeting weight reduction through balanced diets and regular physical activity can significantly decrease both obesity and blood pressure in adolescents. Furthermore, hypertension in adolescents linked to obesity can result in long-term cardiovascular diseases, underscoring the importance of early detection and prevention. Effective management strategies, including lifestyle modification and routine monitoring of body mass index (BMI) and blood pressure, are critical in mitigating these health risks. This review emphasizes the need for public health policies promoting preventive measures such as regular screenings and health education to curb obesity and hypertension in adolescents, reducing their burden on public health systems. Future research should focus on evaluating the effectiveness of multifactorial intervention programs and long-term outcomes in managing obesity-induced hypertension in adolescents.

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The increasing prevalence of central obesity in adolescents is accompanied by an increase in risk factors for cardiovascular disease. The study aims to analyze the relationship between central obesity and the risk of hypertension in obese adolescents, including both male and female subjects. This study was undertaken to provide opportunities for further exploration of the relationship between central obesity and hypertension in adolescents. The study was a retrospective observational study that utilized medical record data from a previous research project entitled "Polimorfisme Gen Adiponectin ADIPOQ +45 T>G, ADIPOQ – 11377 C>G dengan Kadar Adiponektin Pada Remaja Obesitas dan Resiko Sindrom Metabolik." This data was obtained from research conducted on obese adolescents aged 13-18 years in junior and senior high schools in Surabaya and Sidoarjo who met the criteria. The sample comprised 140 obese adolescents, who were then categorized into two groups: those without central obesity and those with central obesity. Statistical data were analyzed using SPSS with the Chi Square test. There is a very strong and significant relationship between central obesity and the risk of hypertension in obese adolescents (p = 0.000; r = 0.373); central obesity and the risk of hypertension in obese male adolescents (p = 0.001; r = 0.587); and central obesity and the risk of hypertension in obese female adolescents (p = 0.003; r = 0.300). The study found a significant relationship between central obesity and hypertension risk in obese adolescents. Adolescents with central obesity were 3.6 times more likely to develop hypertension than those without. Male adolescents with central obesity were 6.5 times more likely to develop hypertension than those without. Female adolescents with central obesity were 2.9 times more likely to develop hypertension

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Waist circumference, body mass index, and skinfold thickness as potential risk factors for high blood pressure in adolescents
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  • Roslina Dewi + 5 more

Background The prevalence of hypertension in children and adolescents has increased with the rising obesity epidemic. Recent studies have found that prevalence of hypertension was higher in obese children or adolescents than in the normal weight ones. Anthropometric measurements such as body mass index (BMI), waist circumference, and skinfold thickness have been used as criteria to determine obesity in children and adolescents. Increased waist circumference has been most closely related to increased blood pressure.
 Objective To compare waist circumference, BMI, and skinfold thickness as potential risk factors for hypertension in adolescents.
 Methods This cross-sectional study was conducted in May 2014 in three senior high schools in Medan, North Sumatera, and included 253 students with normal urinalysis test. All subjects underwent blood pressure, waist circumference, tricep- and subscapular-skinfold thickness (TST and SST), body weight, and body height measurements. The study population was categorized into underweight, normoweight, overweight, and obese, according to four different criteria: waist circumference, BMI, TST, and SST; all variables were analyzed for possible correlations with systolic and diastolic blood pressure.
 Results There were significant positive correlations between systolic blood pressure and waist circumference (OR 7.933; 95%CI 2.20 to 28.65; P=0.011) as well as BMI (OR 4.137; 95%CI 1.16 to 14.75; P=0.041). There were also significant correlations between diastolic blood pressure and waist circumference (OR 3.17; 95%CI 1.83 to 5.51; P=0.002), BMI (P=0.0001; OR=3.69), TST (OR 4.73; 95%CI 2.31 to 9.69; P=0.0001), and SST (OR 3.74; 95%CI 2.35 to 5.94; P=0.0001). Multivariate analysis showed that waist circumference was a predictive factor for systolic blood pressure (OR 9.667), but not for diastolic blood pressure.
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  • Cite Count Icon 3
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  • Oct 30, 2010
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Monitoring and management of hypertension with obesity in adolescents.
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Largely due to the childhood obesity epidemic, there has been an increase in the prevalence of hypertension in children and adolescents. Obesity associated hypertension is the most common hypertension phenotype among adolescents. Approximately 30% of obese adolescents have elevated blood pressure (BP) or hypertension. Updated definitions of elevated BP and hypertension in adolescents are now similar to definitions of BP status in adults. For adolescents ≥13 years of age, elevated BP is 120 to 129/<80 mm Hg. Hypertension, stage 1, is ≥130 to 139/80 to 89 mm Hg, and hypertension, stage 2, is ≥140/90 mm Hg. BP measurements over separate clinic visits are necessary to verify the diagnosis of elevated BP or hypertension. Ambulatory BP monitoring, when available, provides confirmatory data on BP status. Causal mechanisms for obesity associated hypertension include increased sympathetic nervous system activity, increased renal sodium retention secondary to insulin resistance/hyperinsulinemia, and obesity mediated inflammation. The primary treatment for obesity associated hypertension is weight reduction with lifestyle changes in diet and physical activity. Although difficult to achieve, even modest weight reduction can be beneficial. The diet should be rich in fruits, vegetables, fiber, and low-fat dairy with reduction in salt intake. When lifestyle changes are insufficient to achieve BP control, pharmacologic therapy is indicated to achieve a goal BP of <130/80 mm Hg or <90th percentile, whichever is lower. Regular BP monitoring is necessary for ongoing management of obesity associated hypertension in adolescents.

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  • Cite Count Icon 1
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  • May 20, 2016
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  • Ilhaam Esack + 2 more

Background: The prevalence of essential hypertension in children and adolescents has increased dramatically over the past decade attributed to a rising prevalence of obesity, high salt diet and lack of exercise. Traditionally high blood pressure in adolescents required extensive work up to determine a cause, but given the changing demographics this policy needs to be reviewed. Objectives/method: The study aimed describe the risk factors, demographics, target organ damage and aetiology of hypertension in a cohort of young hypertensives (aged 15 - 30 years) referred to a tertiary hypertension clinic at Groote Schuur Hospital, by retrospectively reviewing the folders over a three-month period. Results: Thirty eight patients were identified with a mean age of 22 years. Essential hypertension was diagnosed in 82% of patients, and 71% of patients had a family history of hypertension. The median systolic blood pressure (BP) at first visit was 132 mmHg and diastolic BP 84mmHg. The median BMI was 25.4 kg/m2 and 68% had some form of target organ damage. Twenty six percent were current smokers and 8% had abused metamphetamines. Recognised secondary causes of hypertension were renal artery stenosis (four) and primary aldosteronism (one). Conclusions: In a cohort of young hypertensives patients the dominant cause was essential hypertension. Although the prevalence of obesity was surprisingly low compared to previously published studies, significant lifestyle issues were identified. 68% had target organ damage suggesting the disease was not benign. These preliminary results indicate that larger cohorts need to be studied to develop new policies for assessment and treatment of young people with hypertension in South Africa.

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