Abstract
Introduction:Febrile seizure is among the most common convulsion disorders in children, which strikes 2% to 5% of children between 3 to 60 months of age. Some studies have reported that iron deficiency could be a risk factor for febrile seizure. The present study was conducted to compare the rate of iron deficiency anemia in febrile children with and without seizure.Materials and Methods:This case-control study evaluated 200 children aged 6-60 month in two 100 person groups (febrile seizure and febrile without convulsion) in Kashan. The CBC diff, serum iron and TIBC were done for all of participants. Diagnosis of iron deficiency anemia based on mentioned tests.Results:No significant differences were found in two groups regarding to the age, gender, and the disease causing the fever. The presence of iron deficiency anemia was 45% in the convulsion group and 22% in the group with fever without convulsion. The Chi Square test indicated a significant difference between two groups.Conclusions:The findings suggest that a considerable percentage of children having febrile seizure suffer from iron-deficiency anemia and low serum iron. This means the low serum iron and presence of anemia can serve as a reinforcing factor for the febrile seizure in children.
Highlights
Febrile seizure is among the most common convulsion disorders in children, which strikes 2% to 5% of children between 3 to 60 months of age
The findings suggest that a considerable percentage of children having febrile seizure suffer from iron-deficiency anemia and low serum iron
This means the low serum iron and presence of anemia can serve as a reinforcing factor for the febrile seizure in children
Summary
Febrile seizure is among the most common convulsion disorders in children, which strikes 2% to 5% of children between 3 to 60 months of age. Some studies have reported that iron deficiency could be a risk factor for febrile seizure. The present study was conducted to compare the rate of iron deficiency anemia in febrile children with and without seizure. Some of the recent studies have reported that iron deficiency could be a risk factor for febrile seizure because the latter is more common in children under two years and iron deficiency anemia is common in children of the same age. Since the relationship between iron deficiency and febrile seizure is not yet determined, chance or other unknown factors can be considered as causes (Bidabadi et al, 2009). Considering the above results and since no study has been conducted in Kashan, Iran on the mentioned relationship, the present study was conducted to compare the iron deficiency anemia in the febrile seizure children to those in the febrile patients without convulsion
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