The relationship between capacity management and central venous pressure and blood volume in continuous renal replacement therapy

Abstract

Objective To investigate the correlate of erythrocyte parameters, central venous pressure and blood volume in ICU patients with continuous renal replacement therapy (CRRT), in order to guide the fluid management. Methods The study included two stages.The first stage observed the relation between erythrocyte parameters and central venous pressure (CVP) in ICU patients with CRRT, so that explored the optimum CVP and the optimum erythrocyte parameters.The second stage was to guide the fluid management using the optimum erythrocyte parameters, and analyzed the change of CVP before and after the treatment of fluid expansion or diuresis. Results ①In the first stage, when the class of CVP was >10, RBC, Hb and HCT were significantly lower than it of the classes of CVP 102 g/L, compared with it before treatment, CVP level increased significantly after adding fluid, and the difference had statistical significance(P<0.01). Conclusions CVP has significant negative correlations with the parameters of red blood cells.The corresponding optimum value of red blood cells to the optimum value of CVP had some guiding significance on the fluid management to the patients of continuous kidney substitution therapy. Key words: Central venous pressure; Erythrocyte parameters; Fluid management