Abstract
It has been previously shown that red cell 2,3-diphosphoglycerate (DPG) binds to reduced hemoglobin (Hb) decreasing its affinity for oxygen (O2 and that the in vitro effect of DPG on fetal Hb is less marked than on the adult Hb. The present study on whole blood provides evidence that the in vivo effect of DPG on the O2 affinity of fetal Hb is approximately 40% of that of adult Hb. It also shows that the O2 affinity of fetal blood decreases during gestation and depends on the relative proportions of adult and fetal Hb and on the level of red cell DPG.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
