Abstract
A topic dermatitis is a genetically determined cutaneous affliction characterized by redness, scaling, lichenification, and pruritus, affecting approximately 10% of the population. 1 This allergic disorder is conceptually similar to asthma and allergic rhinitis. Other than a nonspecific spongiosis, there is no pathognomonic histopathology, nor are there diagnostic laboratory parameters for this disorder. A patient with atopic dermatitis demonstrates a constellation of clinical features, most prominent being increased irritability of the skin, intense pruritus, and chronic scratching leading to lichenification. Physiologic abnormalities include specific vasomotor alterations, increased susceptibility to viral, bacterial, and fungal infections, and abnormalities in humoral and cell-mediated immunity.
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