The prospective randomized controlled study about tolerability of transnasal esophagogastroduodenoscopy

Abstract

Objective To study the tolerability and clinical value of transnasal esophagogastroduodenoscopy. Methods A prospective randmnized controlled study has been designed. A total of 120 patients have been enrolled into the study, who were randomly divided into the transnasal group and the oral group （n = 60 cases in each group）. Vomiting frequency, pulse rate, SBP and nasal hemorrhage were recorded delively before the examination,and at every 2-rain till the end of the examination. Results The examination time were （362.9±112.6）s in transnasal group, and （412.1 ± 162.2）s in oral group （t =2.12,P〈 0. 05）. The questionnaire survey showed that patients in transnasal group had less vomitting and cough than in oral group （ t = 2. 26 ,P 〈 0. 05 ）. Fluctuation of SBP and pulse rate in patients undergoing transnasal gastruscope was less than in those undergoing oral procedures （t =2. 36 and 2.58 ,P 〈0. 05）. According to the surey, the patients in transnasal group got less feelings of nausea or vomiting than in oral group. Only 2 （3.3%） patients felt mild pain in nasal cavity. The other 56 （96. 6% ,56/58） felt no pain at all. All the patients would like to accept the transnasal esophagogastroduodenoscopy next time, while half of the patients in oral group disliked peroral gastroscopy. Conclusion The study demonstrates much more tolerability in patients undergoing transnasal esophagogastroduodenoseopy than peroral. Key words: Endoscopy, digestive system; Blood pressure; Pulse; Tolerability