Abstract
Introduction. An association has been demonstrated between intravascular microemboli (ME) and brain injury during cardiopulmonary bypass (CPB) [1]. Surgical, anesthetic, and perfusion techniques should be directed towards reducing the number of ME delivered to the patient [2]. To recommend interventions to reduce embolization, it is important to identify the source, quantity, and composition of ME detected during CPB. We studied the influence of circuit design and vacuum-assisted venous drainage (VAVD) on the generation and propagation of gaseous microemboli (GME) in a model of CPB.
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