Abstract
Summary Clinical and laboratory studies made from the records of 36 patients undergoing total gastrectomy and experiments on 116 totally gastrectomized dogs indicate that 1.Alimentation time is decreased after complete gastrectomy. The amount of carbohydrate, fat and protein absorbed is considerably less than normal. 2.There is a tendency to regain some weight and maintain better nutrition when continuity is maintained between the esophagus and duodenum. This can be accomplished either by direct anastomosis between the esophagus and duodenum or by anastomosis isoperistaltically of a segment of jejunum or colon between the esophagus and duodenum. In human subjects digestion and nutrition appear to be better in patients who have isoperistaltic colon segment transplants and this procedure appears to be worthy of further trial even though it is technically more difficult to perform.
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