Abstract
Aim: To assess maintenance preference and trade-offs for patients with advanced epithelial ovarian cancer. Methods: Patients completed a time trade-off exercise ranking fivemaintenance approaches. Patients' preferred approach was compared with alternatives to determine the progression-free time they would tradeoff to remain on their preferred approach. Results: Of 152 patients (median age 53years, 68% White), 56% chose one of four maintenance medications, mostly to feel proactiveand 44% chose active surveillance. Compared with their preferred approach, patients were willing to trade a mean progression-free time before switching of 2.3months for once-daily oral medications, 3.2months for twice-daily oral medications, 5.5months for intravenous infusions every 3weeks (iv. q3), 6.1months for active surveillanceand 7.5months for iv. q3 and twice-daily oral. Conclusion: Findings highlight the importance of patients' awareness of all maintenance approaches and involving them in the decision-making process.
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