The potential impact of vitamin D on the reduction of C-reactive protein levels in COVID-19 infected patients

Abstract

Introduction and Aim: Vitamin D is a vital component that boosts the immune system and decreases inflammation caused by illness. The topic of Covid-19 is now a subject of controversy and requires extensive investigation to develop effective measures to defend against different versions of the coronavirus. The present study examined the correlation between the positivity of coronavirus disease 2019 (covid-19) tests and the clinical outcomes of vitamin D and CRP levels, which were measured three months before the PCR test, in patients. Materials and Methods: During this retrospective cohort analysis, vitamin D levels were used as the basis for categorizing COVID-19 cases into four distinct categories. Between 0 and 10 ng/ml, 10 to 20 ng/ml, 20 to 30 ng/ml, and greater than 30 ng/ml were the parameters that were used to create groups I through IV, respectively. The levels of vitamin D and C-reactive protein were determined with the assistance of a clinically automated system. Results: Our data indicate that higher levels of vitamin D are associated with a decrease in the severity of Covid-19. Additionally, we observed a negative relationship between vitamin D levels and white blood cells and C-reactive protein (CRP), whereas there was a positive correlation between vitamin D levels and lymphocyte percentage. Conclusion: In accordance with the severity of the Covid-19 infection, the levels of vitamin D and CRP are altered, and these levels have the potential to act as a biomarker for determining the progression of the disease.