Abstract
The obesity paradox has been used to describe the observed phenomenon described by several studies that indicated improved survival for critically ill patients with mild to moderate obesity when compared with their lean counterparts. The study by Arabi and coworkers challenges the obesity paradox concept for critically ill obese patients with septic shock. Their data indicate that obesity, per se, does not significantly improve mortality when outcomes are adjusted for differences in baseline characteristics and sepsis interventions. Further studies are needed to assess the influence of body weight, lean weight, and fat mass for optimizing fluid resuscitation, pharmacotherapy, and nutritional therapy for critically ill patients with sepsis.
Highlights
The obesity paradox has been used to describe the observed phenomenon described by several studies that indicated improved survival for critically ill patients with mild to moderate obesity when compared with their lean counterparts
In the previous issue of Critical Care, Arabi and coworkers examined the effect of obesity upon clinical outcomes following septic shock in a large multicenter cohort study [1]
The worldwide obesity epidemic has led to numerous studies that examined the impact of obesity upon clinical outcomes during critical illness over the past decade
Summary
The obesity paradox has been used to describe the observed phenomenon described by several studies that indicated improved survival for critically ill patients with mild to moderate obesity when compared with their lean counterparts. In the previous issue of Critical Care, Arabi and coworkers examined the effect of obesity upon clinical outcomes following septic shock in a large multicenter cohort study [1]. The worldwide obesity epidemic has led to numerous studies that examined the impact of obesity upon clinical outcomes during critical illness over the past decade.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
