Abstract
T H E U N I T E D S T A T E S Pharmacope ia 1 (U.S.P.) and the National Formulary -~ (N.F.) provide for standardization of essential and therapeutically effective drugs in general use. In order to keep these standards current, interim revisions are issued when needed. Complete new editions are printed every 5 years, and new editions of each became official on Sept. 1, 1965. Drugs considered essential for modern medical practice are listed in these books. Both U.S.P. and N.F. are financed almost entirely from the sale of the books. Each is produced by an organization which is independent of financial support or domination of the government (unique to the United States) and the pharmaceutical industry. However, the standards established by U.S.P. and N.F. are accepted by the Congress of the United States in designating drugs official. These official standards are then enforced by the federal government. The responsibility for establishing standards for new drugs not yet official rests with the Food and Drug Administration and with manufacturers. A total of 404 new official drugs, 156 in
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