Abstract
To enhance the synthesis of the main antigenic coat proteins L1 of high risk oncogenic papillomaviruses types HPV16, HPV18, HPV31 and HPV45, the sequence of the gene encoding the cucumber mosaic virus replicase (RdRP CMV) was inserted into the genetic construct. This inclusion has made possible to increase highly the production of these antigenic proteins to 25—27 µg per 1 mg of total soluble protein of transformed tomato fruit.
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