Abstract
Human infection with SARS-CoV-2, the agent of COVID-19, affects both the central nervous system (CNS) and the peripheral nervous system (PNS) including the muscle (Román GC, SpencerPS, Reis J, et al. The Neurology of COVID-19 Revisited. J Neurol Sci 414 (2020) 116884). This virus is neurogenic and invades the CNS via cranial nerve I, progressing into rhinencephalon and brainstem respiratory centers resulting in irreversible respiratory failure responsible for most of the 6.9 million excess deaths due to this coronavirus (Institute for Health Metrics and Evaluation, University of Washington [www.healthdata.org]).
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