Abstract

The occurrence of Coronary heart disease (CHD) is hard to predict yet , but the assessment of CHD risk for the next ten years is possible . The p rediction of coronary heart disease can be modelled using multi-layer perceptron neural network (MLP-ANN). Prediction model with MLP-ANN ha s either positive or negative CHD output , which is a binary classification. A prediction model with binary classification requires determin ation of threshold value before the classification process which increases the uncertainty in the classification process. Another weakness of the MLP-ANN model is the presence of overfitting. This study propose s a prediction model for coronary heart disease using the duo output artificial neural network ensemble (DOANNE) method to overcome the problems of overfitting and uncertainty of classification in MLP-ANN. This research method wa s divided into several stages, namely data acquisition, pre-processing, modelling into DOANNE, neural network ensemble training with Levenberg-Marquard (LM) algorithm, system performance testing, and evaluation. The results of the study showed that the use of DOANNE-LM method was able to provide a significant improvement from the MLP-ANN method, indicated by the results of statistical tests with p-value <0.05.

Highlights

  • The occurrence of Coronary heart disease (CHD) is hard to predict, the best course of action is an early prediction based on risk factors

  • Similar studies were performed by Kim et al [1] and Kim et al [4] which suggested a prediction model for the incidence of coronary heart disease by using a fuzzy inference system, with the membership function used referring to the Framingham model risk score as well

  • This study proposes the prediction of coronary heart disease by using Duo Output Ensemble Artificial Neural Network (DOANNE)

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Summary

Introduction

The occurrence of Coronary heart disease (CHD) is hard to predict, the best course of action is an early prediction based on risk factors. Existing prediction methods always refers to populations for certain countries, such as Framingham risk score which refers to the population in America or the SCORE for population in Europe This is reinforced in the Kim et al study [1] which mentions the Framingham Risk Score is not quite suitable for the Korean population. Similar studies were performed by Kim et al [1] and Kim et al [4] which suggested a prediction model for the incidence of coronary heart disease by using a fuzzy inference system, with the membership function used referring to the Framingham model risk score as well. The extraction rule algorithm used in Kim et al [1] was C4.5, whereas Kim et al [4] used the CART Both studies are using clinical data for Korean populations. Other models that use knowledge-based Framingham risk score and PROCAM are performed by Khatibi et al

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