Abstract
Endotoxemia was demonstrated in over 90% (28 of 30) of a series of animals subjected to one of four different types of refractory shock. Microscopic study of the lungs showed that the changes characteristic of the lung lesion in shock did not occur unless an endotoxemia developed and persisted until death. When pretreatment by inducing resistance to endotoxin or by intraintestinal administration of nonabsorbable antibiotics prevented the endotoxemia or converted a persistent to a transient endotoxemia, there was a corresponding reduction in the incidence of the lung lesion and the mortality.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
