Abstract
Investigations of the antimitotic action of heavy water were carried out. It was observed that, depending on the conditions of deuteration, cell division in eggs of the sea urchin Arbacia punctulata could be delayed or arrested reversibly. The universality of the antimitotic action of D/sub 2/0 is discussed. The five major types of proposals that were made to account for the biological effects of deuterium enrichment, and particularly for their interference with cell division, are outlined. (M.C.G.)
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