Abstract
LH-dependency in pseudopregnant (PSP) rats was determined by the luteolytic response (fall in serum progesterone, shortening of the diestrus duration, and failure of decidual tissue (DT) formation) to treatment with an antiserum to LH (LHAS). PSP rats hypophysectomized and pituitary autotransplanted on day (d) 2 had no luteolytic response to LHAS treatment on either d 8, 9 or 10, while intact PSP rats, bearing a single pituitary homotransplant from d 2 on, had a pronounced response. The pituitary autotransplant-bearing rats had markedly lower serum LH levels than did intact rats; serum prolactin (PRL) was about 60 ng/ml in both autotransplant- and homotransplant-bearing rats. Treatment of the pituitary autotransplantbearing rat with up to 20 μg ovine LH/d from d 2–8 did not induce LH-dependency. Daily treatment of DT-bearing PSP rats (which normally become LH dependent by d 9), however, with LHAS from d 2–11, or from d 2–5 and again on d 9 did not cause any significant change in progesterone secretion, bu...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
