The influence of assessment and treatment to stable patient with chronic obstructive pulmonary disease by Global Initiative for Chronic Obstructive Lung Disease 2011

Abstract

Objective Study the change and influence of assessment and treatment to stable patient with chronic obstructive pulmonary disease (COPD) by Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2011.Methods Two hundred and sixty-nine stable COPD patients' data were collected including symptom,lung function,acute exacerbation.Analyzing the staging and group according to GOLD 2006 and GOLD 2011.Compare the influence of treatment strategies with the old and new initiative.Results Evaluate patients' symptoms with COPD assessment test (CAT) and modified british medical research council (mMRC).The number of more symptoms patients (B group and D group) was increased by CAT and the total number of patients in C group and D group is similar.Comparing GOLD 2006 with GOLD 2011,44 patients (16.4 ％) in stage Ⅱ needed to change the initial treatment.Risk classification of acute exacerbation is the main factor affecting the group and treatment.FEV1 has positive correlation with the clinical symptoms and the frequency of acute exacerbation of COPD (AECOPD)(P ＜0.01),is also an important objective index of symptom evaluation and risk prognosis.Conclusions Assessing the stable COPD patients with GOLD 2011 is more comprehensive in clinical operation.The results mainly influence the group and treatment of patients in stage Ⅱ and to prognose AECOPD.Though FEV1 is related with the symptom and frequency of AECOPD,but FEV1 is not a sensitive indicator to assess of COPD.The frequency of AECOPD has large impact on COPD risk classification. Key words: Chronic obstructive pulmonary disease; Symptom score; Assessment; Treatment