Abstract
In this experiment rabbits were immunized with bovine alpha-crystallin and their progeny examined for malformations. Slit lamp examination revealed a zonular cataract which was more dense anteriorly. Furthermore in the equatorial area of the lens a marked subcapsular vacuolization was detected. Some vacuoles were also visible in the posterior cortex of the lens. Both inner and outer granular layers of the retinae had lower cell counts. Decrease of nuclei was particularly noticeable in the ganglion cell layer, and many nuclei were pycnotic. This retinal dysplasia is probably the cause of the high b-peaks that were observed during electroretinography. The animals also exhibited other features namely, pupillary rigidity and congenital folding of the retina.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
