Abstract
The aim of the study was to study the influence of adherence to treatment on myocardial dysfunction in elderly and senile patients with ischemic heart disease (IHD) and chronic heart failure (CHF). Material and methods. The study included 86 patients with ischemic heart disease (CHD) of older age groups admitted to hospital treatment because of the progression of CHF: 21 patients — 65 to 74 years, 65 patients — 75 to 89 years. A standard clinical study, echocardiography with global longitudinal strain assessment (GLS), and a Morisky-Green test were performed. Results . It is established that in the group of persons of senile age there is a lower adherence to treatment and more pronounced structural and functional changes in the myocardium. The following correlations were revealed: total score of the Morisky-Green test with the left ventricular end-diastolic volume (r = -0.33, p <0.05), with the E/e’ (r = -0.37, p <0.05), with GLS (r = 0.53). Conclusion. The findings indicate a lower adherence of the senile patients on treatment of IHD and CHF in comparison with the elderly. Low adherence to therapy, as well as postinfarction cardiosclerosis, can apparently be considered as one of the factors contributing to the progression of myocardial dysfunction.
Highlights
The Russian Archives of Internal Medicine No 1 2018 clinical study, echocardiography with global longitudinal strain assessment (GLS), and a Morisky-Green test were performed
The aim of the study was to study the influence of adherence to treatment on myocardial dysfunction in elderly and senile patients with ischemic heart disease (IHD) and chronic heart failure (CHF)
The study included 86 patients with ischemic heart disease (CHD) of older age groups admitted to hospital treatment because of the progression of CHF: 21 patients — 65 to 74 years, 65 patients — 75 to 89 years
Summary
1 — СПб ГБУЗ «Госпиталь для ветеранов войн», Санкт-Петербург, Россия 2 — ФГБОУ ВО «Северо-Западный государственный медицинский университет им. Целью исследования было изучение влияния приверженности терапии на дисфункцию миокарда у лиц пожилого и старческого возраста с ишемической болезнью сердца и хронической сердечной недостаточностью. В исследование были включены 86 больных ишемической болезнью сердца старших возрастных групп, поступивших на стационарное лечение в связи с прогрессированием хронической сердечной недостаточности: 21 пациент — от 65 до 74 лет, 65 пациентов — от 75 до 89 лет. Установлено, что в группе лиц старческого возраста имеют место более низкая приверженность к лечению и более выраженные структурно-функциональные изменения миокарда. Ключевые слова: ишемическая болезнь сердца, сердечная недостаточность, приверженность терапии, пожилой и старческий возраст, дисфункция левого желудочка, эхокардиография, глобальная продольная деформация миокарда. ЦИЕНТОВ ПОЖИЛОГО И СТАРЧЕСКОГО ВОЗРАСТА С ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА И СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТЬЮ.
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