Abstract
Large bone defects are a challenging situation for surgeons, either in acute management, either in case of a nonunion or a septic nonunion. Different treatment proposals have been made since a long time using autologous cancellous bone graft, open-air cancellous Papineau grafting, free vascularized bone transfer, bone transport or allograft (1,2,3). Since 2000, the induced membrane technique, so-called the Masquelet technique, has been described for treatment of such very difficult cases that we can express as treatment of critical sized bone defects (4,5). In the following, we’ll try to give as much details as possible for a positive result when using the induced membrane technique. Clinical based algorithm will be emphasized.
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