Abstract
Objective: to analyze intraoperative and postoperative complications in patients who underwent combination surgeries for advanced ovarian cancer.Materials and methods. This retrospective study included patients that underwent primary or interval cytoreductive combination surgeries for advanced (grade III–IV) ovarian cancer at N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia between 2000 and 2017.Results. We analyzed medical records of 144 patients with grade III–IV ovarian cancer who underwent combination surgery at some stage of their treatment. Almost two-thirds of patients (64.8 %) had complete or optimal volume of surgery. Intraoperative complications were registered in 7 % of patients (n = 10), while postoperative complications were observed in 38.2 % of cases (n = 55). The postoperative death rate was 0.7 % (n = 1).Conclusions. Higher frequency of complete and optimal cytoreduction, as well as acceptable level of intra- and postoperative complications confirm the need for combination surgeries in patients with advanced ovarian cancer. Aggressive surgical tactics should be used only in specialized cancer hospitals with the involvement of a multidisciplinary team that includes cancer surgeons and anesthesiologists in order to improve both short-term and long-term treatment outcomes in patients with advanced ovarian cancer.
Highlights
Цель исследования – оценка интра- и послеоперационных осложнений у больных, перенесших комбинированный объем хирургических вмешательств по поводу распространенного рака яичников
Higher frequency of complete and optimal cytoreduction, as well as acceptable level of intra- and postoperative complications confirm the need for combination surgeries in patients with advanced ovarian cancer
9. Bartl T., Schwameis R., Stift A. et al Predictive and prognostic implication of bowel resections during primary cytoreductive surgery in advanced epithelial ovarian cancer
Summary
В ретроспективное исследование включены пациентки, которым выполнены первичные или интервальные циторедуктивные операции в комбинированном объеме по поводу распространенного (III–IV стадия) рака яичников (РЯ) в ФГБУ «Национальный медицинский исследовательский центр онкологии им. Непосредственные результаты комбинированных операций у больных распространенным раком яичников: опыт ФГБУ «Национальный медицинский исследовательский центр онкологии им. Что резек- нение комбинированных циторедуктивных операций ция различных отделов кишечника выполнялась позволяет значительно улучшить как непосредствену 205 (77 %) больных, из них резекция ректосигмоидно- ные, так и отдаленные результаты лечения пациенток го отдела толстой кишки – у 148 (57 %), илеоцекальная с поздними стадиями РЯ [2,3,4,5]. Экстирпация матки с придатками, удаление большого сальника, резекция различных отделов кишки
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