Abstract

inks between single genes and behavior in the fruit flyDrosophila melanogaster have been studied since the 1970s, but scientists have only recently begun making such connections in mammals by studying the genes that control the circadian clock, the body's daily sleep and activity cycle. The investigators are concentrating on these genes because the clock's cellular actions take place in a well-understood region of the mammalian brain and because genes with similar functions have been characterized for

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