Abstract
The [Cu(amikacin)(H 2O) 3] complex was prepared and characterized by elemental analysis, TGA and spectroscopic techniques ( viz. IR, electronic and EPR spectra). The spectral results obtained indicate distorted octahedral geometry around the Cu(II) ion. The orbital reduction factors K∥ and K⊥ have been calculated. Amikacin can be estimated indirectly by atomic absorption spectroscopy using carbonate as an auxiliary ligand. The complex shows biological activity towards six organisms. Amikacin is biologically active towards Sarcina lutea, whereas the Cu(II)-amikacin complex is biologically inactive.
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