Abstract

The 15N-abundance was determined in urine from normal persons in nitrogen balance up to 360 hours after administration of 15N-labelled glycine. It is shown that the 15N-abundance in excess in urine with good approximation follows the equation: a = a 1e − B 1 t + a 2e − B 2 t + a 3e − B 3 t By integration of this equation an expression is obtained which can render the cumulative excretion of 15N. Two different models are set up for the treatment in the organism of administered nitrogen both of which lead to equations which agree with the empirical expressions for 15N-abundance in urine and the cumulative excretion of 15N. By means of the empirically determined constants the flows and the sizes of three homogeneous nitrogen pools in the models have been calculated.

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