Abstract

Introduction: Bleeding is an important consideration in breast surgery as the operation site is confined and any uncontrolled bleeding might result in skin necrosis, which in turn delays the healing. Tranexamic acid (TXA) is a synthetic amino acid that blocks plasminogen from being converted to the enzyme plasmin. Plasmin works by breaking down fibrin already formed in blood clots resulting in fibrinolysis and therefore clot lysis. It is used safely in several medical and surgical settings and has been demonstrated to effectively reduce perioperative blood loss without any significant safety concerns.

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