Abstract

The effects of sympathetic nerve activation j on tracer disappearance rate and local blood content J in the cat nasal mucosa were studied by measuring local disappearance of 125I− and changes in gross pulse rate from 131I-labelled serum albumin monitored over i the nose. Major changes in the tracer disappearance rate were seen in the frequency range of 0.5-6.0 imp/sec while similar changes in the local blood content occurred at 0.1-0.5 imp/sec, indicating a functional differentiation in the vasoconstrictor control of (the exchange and capacitance vessels during low sympathetic tone. The observed responses were shown to ' be due to activation of sympathetic adrenergic nerves and receptors of the a-type. No evidence of vasodilator influence due to stimulation of β-receptors or sympathetic cholinergic vasodilator fibers was found 1

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