Abstract
The Metopirone (Metp), tested on the isolated and beating heart of Bufo vulgaris or on the homogenates of this organ revealed: (1) an excito-metabolic activity, which manifests itself in variations of the contraction force of the cardiac muscle and in the potentiation both of the temporary repolarization phenomena and of the tissue phosphorylase; (2) the tendency to favor the penetration of 2-deoxyglucose (2-DG) into myocardial cells.
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