Abstract

The higher level of zinc concentration in tumorous bone tissue of osteosarcoma have been reported in previous paper.The present study was performed in order to clarify the effect of zinc concentration on bone growth in rat.The increasing rate of body weight for 6 weeks, longitudinal length and zinc concentration of femur in rat were compared among the following three groups; A group: administrated with zinc deficient diet for 6 weeks, B group: 100p.p.m. zinc supplemented diet, C group: 500p.p.m. zinc supplemented diet.Both of the increasing rate of body weight (%) and the longitudinal length of femur (cm) in B and C group were significantly higher than those in A group.

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