Abstract
1. 1. Pyridoxine and pyridoxal caused a decreased mucosal-to-serosal and increased serosal-to-mucosal alanine flux across the isolated intestine of the fresh-water turtle. 2. 2. The intestinal cell alanine accumulation is reduced by pyridoxine, and cell Na and K concentrations in the presence of pyridoxine were not different from those of controls. 3. 3. Alanine influx from the mucosal solution into the cell across the brushborder membrane was not influenced by vitamin B 6. 4. 4. The findings suggest that pyridoxine and pyridoxal act mainly on the efflux processes of alanine across the cell barriers. The efflux across the mucosal barrier is increased and the efflux across the serosal barrier is decreased.
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