Abstract

The beta-sympathomimetic agent ritodrine exerts its tocolytic effects via its beta-2 receptor effects on uterine smooth muscle. However, it also produces maternal cardiovascular effects by means of its beta-1 receptor stimulating effects. Since ritodrine has a half-life of 32±21 minutes its effects may persist when anesthesia is required in pregnant women after failure of tocolysis. The current study was designed to assess the effects of various vasopressors on uterine artery blood flow velocity (UBFV) after ritodrine infusion.

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