Abstract
In the present study emphasis was placed on the circulatory pattern of the low-pressure system when sodium nitroprusside (Na-NP) as vasodilatator and norepinephrine (NE) as a vasoconstrictive agent were given to anesthetized dogs. Mean arterial pressure, cardiac output, central venous pressure, peripheral venous pressure and plasma volume were measured. 12 animals received Na-NP and 11 animals received NE infusions which lasted between 80 and 90 min. The respective dosages were on the average 7.8 μg·kg−1·min−1 and 1.16 μg·kg−1·min−1.
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